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1

Design, Synthesis, Evaluation, and Structure of Vitamin D Analogues with Furan Side Chains

Dr. Ramón Fraga, Dr. Flavia Zacconi, Dr. Fredy Sussman, Dr. Paloma Ordóñez-Morán, Prof. Dr. Alberto Muñoz, Tiphaine Huet, Dr. Ferdinand Molnár, Prof. Dr. Dino Moras, Prof. Dr. Natacha Rochel, Prof. Dr

Journal:

Chemistry - A European Journal

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

2

Autolysosomal β-catenin degradation regulates Wnt-autophagy-p62 crosstalk

Petherick, Katy J, Williams, Ann C, Lane, Jon D, Ordóñez-Morán, Paloma, Huelsken, Joerg, Collard, Tracey J, Smartt, Helena JM, Batson, Jennifer, Malik, Karim, Paraskeva, Chris, Greenhough, Alexander

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 3.77 MB

english, 2013

3

The Wnt antagonist DICKKOPF-1 gene is induced by 1 ,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells

Aguilera, O., Pena, C., Garcia, J. M., Larriba, M. J., Ordonez-Moran, P., Navarro, D., Barbachano, A., Lopez de Silanes, I., Ballestar, E., Fraga, M. F., Esteller, M., Gamallo, C., Bonilla, F., Gonzal

Journal:

Year:

2007

Language:

english

File:

PDF, 854 KB

english, 2007

4

Designer matrices for intestinal stem cell and organoid culture

Gjorevski, Nikolce, Sachs, Norman, Manfrin, Andrea, Giger, Sonja, Bragina, Maiia E., Ordóñez-Morán, Paloma, Clevers, Hans, Lutolf, Matthias P.

Journal:

Year:

2016

Language:

english

File:

PDF, 6.12 MB

english, 2016

5

The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer

Pálmer, Héctor G, Larriba, María Jesús, García, José Miguel, Ordóñez-Morán, Paloma, Peña, Cristina, Peiró, Sandra, Puig, Isabel, Rodríguez, Rufo, de la Fuente, Ricardo, Bernad, Antonio

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 1.12 MB

english, 2004

6

RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells

Ordonez-Moran, P., Larriba, M. J., Palmer, H. G., Valero, R. A., Barbachano, A., Dunach, M., de Herreros, A. G., Villalobos, C., Berciano, M. T., Lafarga, M., Munoz, A.

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 3.89 MB

english, 2008

7

Lrig1: a new master regulator of epithelial stem cells

Ordóñez-Morán, Paloma, Huelsken, Joerg

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 272 KB

english, 2012

8

Complex metastatic niches: already a target for therapy?

Ordóñez-Morán, Paloma, Huelsken, Joerg

Journal:

Current Opinion in Cell Biology

Year:

2014

Language:

english

File:

PDF, 320 KB

english, 2014

9

Vitamin D and cancer: an update of in vitro and in vivo data

Ordonez-Moran, Paloma,

Journal:

Frontiers in Bioscience

Year:

2005

Language:

english

File:

PDF, 2.90 MB

english, 2005

10

Nuclear receptors: Genomic and non-genomic effects converge

Ordóñez-Morán, Paloma, Muñoz, Alberto

Journal:

Year:

2009

Language:

english

File:

PDF, 258 KB

english, 2009

11

687 Beta-catenin Confers Resistance to PI3K and AKT Inhibitors and Subverts FOXO3a to Promote Metastasis in Colon Cancer

S.P. Tenbaum, P. Ordóñez-Morán, I. Puig, I. Chicote, O. Arqués, A. Vivancos, J. Baselga, J. Tabernero, A. Muñoz, H.G. Palmer

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 53 KB

english, 2012

12

-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells

Smartt, H. J. M., Greenhough, A., Ordonez-Moran, P., Talero, E., Cherry, C. A., Wallam, C. A., Parry, L., Al Kharusi, M., Roberts, H. R., Mariadason, J. M., Clarke, A. R., Huelsken, J., Williams, A. C

Journal:

Year:

2012

Language:

english

File:

PDF, 749 KB

english, 2012

13

SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity

Barbáchano, A, Ordóñez-Morán, P, García, J M, Sánchez, A, Pereira, F, Larriba, M J, Martínez, N, Hernández, J, Landolfi, S, Bonilla, F

Journal:

Year:

2010

Language:

english

File:

PDF, 2.28 MB

english, 2010

14

Synthesis, Structure, and Biological Activity of des-Side Chain Analogues of 1α,25-Dihydroxyvitamin D3 with Substituents at C18

Dr. Lieve Verlinden, Prof. Annemieke Verstuyf, Dr. Guy Eelen, Prof. Roger Bouillon, Dr. Paloma Ordóñez-Morán, Dr. María Jesús Larriba, Prof. Alberto Muñoz, Dr. Natacha Rochel, Dr. Yoshiteru Sato, Dr.

Journal:

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

15

SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer

Ordóñez-Morán, P, Irmisch, A, Barbáchano, A, Chicote, I, Tenbaum, S, Landolfi, S, Tabernero, J, Huelsken, J, Muñoz, A, Pálmer, H G

Journal:

Year:

2014

Language:

english

File:

PDF, 10.34 MB

english, 2014

16

β-catenin negatively regulates expression of the prostaglandin transporter PGT in the normal intestinal epithelium and colorectal tumour cells: a role in the chemopreventive efficacy of aspirin?

Smartt, H J M, Greenhough, A, Ordóñez-Morán, P, Al-Kharusi, M, Collard, T J, Mariadason, J M, Huelsken, J, Williams, A C, Paraskeva, C

Journal:

British Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 718 KB

english, 2012

17

β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer

Tenbaum, Stephan P, Ordóñez-Morán, Paloma, Puig, Isabel, Chicote, Irene, Arqués, Oriol, Landolfi, Stefania, Fernández, Yolanda, Herance, José Raúl, Gispert, Juan D, Mendizabal, Leire, Aguilar, Susana,

Journal:

Nature Medicine

Year:

2012

Language:

english

File:

PDF, 3.35 MB

english, 2012

18

The effects of 1,25-dihydroxyvitamin D3 on colon cancer cells depend on RhoA-ROCK-p38MAPK-MSK signaling

Paloma Ordóñez-Morán, Silvia Álvarez-Díaz, Noelia Valle, María Jesús Larriba, Félix Bonilla, Alberto Muñoz

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2010

Language:

english

File:

PDF, 994 KB

english, 2010

19

The inhibition of Wnt/ -catenin signalling by 1 ,25-dihydroxyvitamin D3 is abrogated by Snail1 in human colon cancer cells

Larriba, M. J., Valle, N., Palmer, H. G, Ordonez-Moran, P., Alvarez-Diaz, S., Becker, K.-F., Gamallo, C., de Herreros, A. G., Gonzalez-Sancho, J. M., Munoz, A.

Journal:

Endocrine Related Cancer

Year:

2007

Language:

english

File:

PDF, 545 KB

english, 2007

20

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150

A. Barbáchano, A. Fernández-barral, F. Pereira, M. F. Segura, P. Ordóñez-morán, E. Carrillo-de Santa Pau, J. M. González-sancho, D. Hanniford, N. Martínez, A. Costales-carrera, F. X. Real, H. G. Pálme

Year:

2015

Language:

english

File:

PDF, 4.39 MB

english, 2015

21

RhoA-ROCK and p38MAPK-MSK1 Mediate Vitamin D Effects on Gene Expression, Phenotype, and Wnt Pathway in Colon Cancer Cells

Paloma Ordóñez-Morán, María Jesús Larriba, Héctor G. Pálmer, Ruth A. Valero, Antonio Barbáchano, Mireia Duñach, Antonio García de Herreros, Carlos Villalobos, María Teresa Berciano, Miguel Lafarga and

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 3.98 MB

english, 2008

22

Enhanced Rate of Acquisition of Point Mutations in Mouse Intestinal Adenomas Compared to Normal Tissue

Lugli, Natalia, Dionellis, Vasilis S., Ordóñez-Morán, Paloma, Kamileri, Irene, Sotiriou, Sotirios K., Huelsken, Joerg, Halazonetis, Thanos D.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.27 MB

english, 2017

23

HOXA5 Counteracts Stem Cell Traits by Inhibiting Wnt Signaling in Colorectal Cancer

Ordóñez-Morán, Paloma, Dafflon, Caroline, Imajo, Masamichi, Nishida, Eisuke, Huelsken, Joerg

Journal:

Year:

2015

Language:

english

File:

PDF, 7.19 MB

english, 2015

24

Intestinal Stem Cell Niche Insights Gathered from Both In Vivo and Novel In Vitro Models

Gjorevski, Nikolce, Ordóñez-Morán, Paloma

Journal:

Stem Cells International

Year:

2017

Language:

english

File:

PDF, 2.68 MB

english, 2017

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